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发明授权
CN102102118B 一种L-鸟氨酸-L-天门冬氨酸盐的制备方法 失效 - 权利终止 转让

一种L-鸟氨酸-L-天门冬氨酸盐的制备方法
摘要：
本发明涉及一种L-鸟氨酸-L-天门冬氨酸盐的制备方法，通过精氨酸酶转化生产L-鸟氨酸-L-天门冬氨酸盐，包括以下步骤：(1)固定化酶的制备，(2)转化条件的优化，(3)产物提取和精制工艺步骤。与现有技术相比，本发明具有生产成本低、生产条件温和、转化体系中杂质较少、工艺步骤简单、生产操作安全、纯度高，每升反应溶液中含有300-320g的L-鸟氨酸-L-天门冬氨酸盐，产量高、精氨酸的转化率达95％以上等优点。
摘要（英）：

The invention relates to a method for preparing L-ornithine-L-aspartate salt. The L-ornithine-L-aspartate salt is produced through conversion of arginase. The method comprises the following process steps of: (1) preparing immobilized enzyme; (2) optimizing conversion conditions; and (3) extracting product and refining. Compared with the prior art, the method has the advantages that: production cost is low, the production conditions are mild, impurities in a conversion system are a few, the process steps are simple, the production operation is safe, the purity is high, 300 to 320g of L-ornithine-L-aspartate salt is contained in each liter of reaction solution, the yield is high, the conversion rate of arginase is over 95 percent and the like.

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