利索-全球专利检索

  1. 登录
  2. 注册
发明公开
CN102143753A 含有15,15-二氟前列腺素F2α衍生物作为有效成分的毛发生长促进剂 失效 - 权利终止

含有15,15-二氟前列腺素F2α衍生物作为有效成分的毛发生长促进剂
摘要：
本发明提供15，15-二氟前列腺素F2α衍生物的新的医药用途。为了发现15，15-二氟前列腺素F2α衍生物的新的医药用途进行了深入研究，结果发现在作为15，15-二氟前列腺素F2α衍生物之一的他氟前列素的以开角型青光眼或高眼压症患者为对象的欧洲Ⅲ期临床试验中，所述他氟前列素具有使睫毛生长、硬化及变色作用，即，具有毛发(睫毛)生长促进效果。因此，15，15-二氟前列腺素F2α衍生物作为毛发生长促进剂是有用的，期待作为脱毛症等与毛发有关的疾病的预防或治疗剂及以生发·育发·增发·养发等为目的的毛发护理产品或毛发化妆品的有效成分是有用的。
摘要（英）：

The present invention provides a new pharmaceutical application of a 15,15-difluoroprostaglandin F 2alpha derivative. As a result of intensive studies in order to find a new pharmaceutical application of a 15,15-difluoroprostaglandin F 2alpha- derivative, it was found that, in a European Phase III clinical, trial for tafluprost, one of the 15,15-difluoroprostaglandin F 2alpha derivatives, with patients with open-angle glaucoma or ocular hypertension, tafluprost has actions of growing eyelashes, making eyelashes thicker, and changing the color thereof, that is, has an effect of promoting the growth of hair (eyelashes). Therefore, a 15, 15-difluoroprostaglandin F 2alpha derivative is useful as a hair growth promoting agent, and is expected to be useful as an active ingredient of a preventive or therapeutic agent for a disease associated with hair such as alopecia and a hair care product or a hair cosmetic product for regrowing hair, growing hair, increasing hair density, nourishing hair, or the like.

公开/授权文献
0/0