The invention discloses a differential boxing method and relates to the field of goods storage. The differential boxing method comprises the following steps: a step 1 of predicting an average weight value according to a weight value of the current batch of tobacco leaf incoming materials and batches which need to be divided; a step 2 of setting a fixed weight value of each box of filled tobacco leaves according to the size of the average weight value; a step 3 of setting a differential factor according to the foregoing conditions; a step 4 of filling the tobacco leaves in the range of the average weight value into tobacco boxes according to the weight determined by the fixed weight value and the differential factor, and uniformly dividing the tobacco boxes into the divided batches; and a step 5 of filing the tobacco leaves outside the range of the average weight value into boxes according to the fixed weight value, and uniformly dividing the boxes into the divided batched. In the scheme, the problem of balanced division of the batches is solved by utilizing differential factor boxing. The differential boxing method is beneficial for the stabilization of product quality and is alsobeneficial for transverse grouped processing of a module and application and popularization of a leaf box storage process.