The invention discloses a reed residue squeezing machine which comprises a transmission motor, a bearing pedestal, an extruding screw shaft, a shell, a filtrate screen cylinder and an anti-skidding cylinder and is characterized in that the extruding screw shaft adopts a variable-diameter variable-pitch structure and is a tampered shaft. The reed residue squeezing machine is developed and designed aiming at biomass raw materials such as wet reed residue and the like, has specific structure, high extrusion efficiency, achieves more than 50% of dehydration dryness, not only can be successfully applied to the dehydration and drying of the wet reed residue, but also can realize the high-efficiency dehydration of other biomass garbage such as sawdust, waste residue, sludge and the like, has wide application range, solves the difficult problem of a more prominent equipment technology and fills the gap.