Provided are a protector capable of discharging water to the outside, and a wire harness including in the structure thereof the protector. A water drain hole (46) is formed as a portion from which water collecting in an electric wire housing section (45) is discharged to the outside. The water drain hole (46) is formed so as to penetrate through the electric wire housing section (45) toward the rear of a vehicle. The water drain hole (46) is formed so as to gradually tilt from the electric wire housing section (45) toward the ground surface. The water drain hole (46) is a through hole formed at a position near an end of a vehicle interior protective member (27). The water drain hole (46) is formed and located in that portion of the wire harness which is the closest to the ground surface.