The invention discloses an intelligent management system of a wireless anti-slip device and relates to a management system of aanti-slip device for railway locomotive vehicles. The intelligent management system comprises a anti-slip device storage cabinet which is used for storing, fixing and managing an anti-slip device and automatically identifying the access state of the anti-slip device, a handheld mobile terminal which has functions of automatic-induction card reading and automatic storage, an anti-slip device host which can automatically receive and display the using situation of the anti-slip device and record the assess status of the anti-slip device, and a signal tower display terminal which can automatically receive and display the arrangement and removal state of the anti-slip device on a station yard circuit, wherein the anti-slip device storage cabinet and the signal tower display terminal are connected with the anti-slip device host through a wireless data transmission device, and the handheld mobile terminal is connected with the anti-slip device host through GSM (global system for mobile communication)/GPRS (general packet radio service) wireless transmission. By adopting the advanced wireless data transmission technology and information management technology, the intelligent management system has high reliability, strong anti-interference capability, is simple, practical and convenient to operate, thereby greatly reducing administrative management and operation recording work and realizing more scientific and effective anti-slip device management.