The invention relates to a toxin-expelling skin-nourishing health-care product and a preparation method thereof. The health-care product comprises the following raw material components in part by weight: 20 to 100 parts of flower, 1,000 parts of white spirit, 15 to 40 parts of bifidus factor, 10 to 30 parts of Chinese wolfberry, 5 to 15 parts of ginseng, 15 to 20 parts of Chinese angelica, 5 to 10 parts of longan, 5 to 15 parts of astragalus, 5 to 10 parts of eucommia bark, 5 to 25 parts of Chinese yam, and 10 to 15 parts of liquoric root. The toxin-expelling skin-nourishing health-care product is prepared by the following steps of: mixing the raw materials, and processing. The toxin-expelling skin-nourishing health-care product has the fragrance of flowers, and also has the effects of relaxing the bowls, expelling toxin and the like; meanwhile, the toxin-expelling skin-nourishing health-care product can also achieve the effects of beautifying and nourishing skin. By the method, serial products of toxin-expelling skin-nourishing tea, toxin-expelling skin-nourishing oral liquid and toxin-expelling skin-nourishing wine can be prepared according to different tastes and functions of the flowers.