The invention discloses a large-grid distributed real-time database system and a data management method thereof. The system comprises a wide-area distributed real-time database storage system (1), a globally unique identifier analysis and service positioning system (2), a sub-system internal real-time data access system (3) and a distributed service agent (4), wherein the wide-area distributed real-time database storage system is used for storing real-time data in a wide-area distributed environment and efficiently indexing the real-time data by a globally unique identifier; the globally unique identifier analysis and service positioning system is used for analyzing the globally unique identifier and positioning a logical space in which the real-time data is accommodated and a corresponding service agent by using the globally unique identifier; the sub-system internal real-time data access system provides service for the network access of the real-time data in a sub-system on the basis of the wide-area distributed real-time database storage system; and the distributed service agent is connected with the globally unique identifier analysis and service positioning system and the sub-system internal real-time data access system and provides the service for cross-area and cross-system sharing and access of the real-time data. By the invention, the sharing and management of the mass real-time data in the wide-area distributed network environment can be realized.