The invention discloses a pipe-sealing bag-making filling machine which comprises a rack, a tube-feeding device, a bag-supplying device, a heat-seal device, a filling device, a sealing device, a bag-withdrawing device and a conveying device; the conveying device comprises a transmission chain on which a plurality of hanging panels are mounted at equal intervals, and an opening is arranged on eachhanding panel. The machine provided by the invention is characterized in that one side of each hanging panel is articulated with the transmission chain; the transmission chain is sequentially provided with a tube-feeding station, a bag-supplying station, a heat-seal station, a filling station, a sealing station and a bag-withdrawing station; a first turnover mechanism capable of turning each hanging panel into a vertical state from a horizontal state is arranged between the tube-feeding station and the bag-supplying station; and a second turnover mechanism capable of turning each hanging panel into the horizontal state from the vertical state is arranged between the heat-seal station and the filling station, and a hanging panel trough capable of holding the hanging panels in the vertical state is arranged between the first turnover mechanism and the second turnover mechanism. The pipe-sealing bag-making filling machine integrates the bag-making and material-filling functions and is simple and compact in structure, less in volume and low in fault rate.