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发明授权
CN102257000B 新型志贺氏菌蛋白抗原及方法 有权

新型志贺氏菌蛋白抗原及方法
摘要：
本发明涉及来自志贺氏菌的蛋白抗原IcsP2和SigA2，所述蛋白抗原IcsP2和SigA2在众多志贺氏菌类型和种中很常见，在作为疫苗给药时，能够防止志贺氏菌病或其它肠道感染。另外，本发明涉及在志贺氏菌种和肠侵袭性大肠杆菌(EIEC)中常见的抗原。本发明还涉及针对这些抗原产生的抗体的用途及DNA探针在诊断志贺氏菌和EIEC感染中的用途。
摘要（英）：

The present invention relates to protein antigens IcsP2 and SigA2 from Shigella that are common among numerous Shigella types and species and which can protect against shigellosis or other enteric infections when administered as vaccines. In addition, the present invention relates to antigens that are in common between Shigella species and enteroinvasive Escherichia coli (EIEC). The invention also relates to the use of antibodies raised against these antigens and of DNA probes for use in the diagnosis of Shigella and EIEC infections.

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