The invention discloses a multi-channel laser coating method for preparing a cerium dioxide seed layer. According to the invention, a multi-channel transmission device is adopted; the cerium dioxide seed layer is prepared on an annealed nickel-tungsten metal base band through a multi-channel laser evaporation coating method; in the coating process, the coating speed of the cerium dioxide seed layer on the base band is greatly accelerated through winding repeatedly the nickel-tungsten metal base band on a roll shaft and passing through a coating region, can reach over one hundred meters per hour and is suitable for kilometer-level long band preparation; the atmosphere adopted when the method is used for coating is a mixed gas of argon and hydrogen, the argon is am inert gas and mainly plays a buffer function, and the hydrogen has the main function of consuming residual oxygen in the coating cavity in the coating process, so that baseband surface oxidation which can be generated under the condition of high-temperature coating and affects the orientation of the cerium dioxide seed layer is avoided; in addition, the coating atmosphere is the mixed gas of argon and hydrogen so that therequirement on base vacuum degree of a coating system can be greatly reduced, the equipment investment is saved, and the band material cost is reduced.