The invention relates to positioning information anti-counterfeiting laser powder and a preparation method thereof. Each particle of the positioning information anti-counterfeiting laser powder comprises a vacuum evaporation layer or a medium coating layer and a die pressing layer with anti-counterfeiting information which are arranged in a laminated way. Each particle of the positioning information anti-counterfeiting laser powder is provided with special laser hologram image-text information. The laser hologram image-text information can be continuous, namely can be positioned on each particle at random; and the image-text information can also be fixed. The powder can be processed on a product or a package after being prepared into printing ink, varnish, gloss oil, resin and the like, and can also be directly used for a plastic extrusion molding product; the laser hologram image-text information which is contained in the powder can be viewed through a high-multiplying power magnifier; and each product can be prepared into unique special laser hologram image-text information, has an extremely excellent anti-counterfeiting function and is easy to determine.