The invention discloses a compressed natural gas pipe and a manufacture method thereof, belonging to the technical field of compressed natural gas pipes and manufacture methods thereof. The compressed natural gas pipe is mainly technically characterized by comprising an inner layer, a reinforcing layer, a static conducting layer and an outer protection layer, wherein the inner layer comprises an inner lining layer, a blocked layer and an outer lining layer from inside to outside; the inner lining layer and the outer lining layer are comprise the following materials in parts by weight: 100 parts of PA11 or PA12 (polyamide), 3-5 parts of lubricating agent, 4-5 parts of plasticizer and 7-8 parts of heat stabilizer; and the blocked layer comprises the following materials in parts by weight: 100 parts of EVOH (ethylene-vinylalcohol copolymer), 2-2.4 parts of plasticizer and 1-1.2 parts of heat stabilizer. The compressed natural gas pipe produced by adopting the method has strong gas tightness, can effectively prevent high-pressure natural gas from leaking to cause gas leakage, explosion and other accidents, and has the advantages of long service life of above 6months which are above 2 times of that of the traditional natural gas pipe, working pressure of more than or equal to 35Mpa, strong static conducting capacity and capability of preventing from firing or exploding.