The invention discloses oral liquid for treating a hypertensive cardio-cerebrovascular syndrome, wherein the oral liquid is good for making up defects existing in other methods and is prepared from the following medicinal herbs: 30-50 grams of golden thread, 40-60 grams of dogbane leaf, 40-60 grams of saffron crocus, 20-40 grams of hairy deerhorn, 10-30 grams of root of red-rooted salvia, 20-40 grams of myrrh, 40-60 grams of astragalus root, 30-50 grams of liquorice, 20-40 grams of hawthorn, 40-60 grams of rhodiola rosea, 20-40 grams of slenderstyle acanthopanax root-bark, 20-40 grams of Chinese yam, 20-40 grams of propolis, 20-40 grams of honey, and 3000-6000 grams of yellow rice wine. A preparation method of the oral liquid comprises the following steps of: step 1, decocting: putting the screened medicinal herbs and the yellow rice wine into a porcelain pot according to the regulated proportion for decoction, and after boiling the liquid medicine, decocting with slow fire for 1 hour; step 2, storing: sealing the decocted medicinal herbs and the liquid medicine together in the porcelain pot and storing in a cellar for 7 days; step 3, filtering: filtering the medicinal herbs stored for 7 days and filtering out dreg; and step 4, filling: filling 120 grams per bottle and packaging 20 bottles per box.