The invention relates to a cartridge drive unit which is connected with a cartridge body. The cartridge drive unit comprises the following parts: a connection driving part which is used for connecting with the end portion of the cartridge body, comprises a plurality of claws and is provided with a first powder outlet; a sealing part which is arranged in the connection driving part and provided with a second powder outlet; a powder outlet opening part which is arranged in the connection driving part and fixedly connected with the sealing part; a clutch which comprises a housing, a central iron shaft extending from the housing and a rotation driving unit that is sleeved on the central iron shaft, wherein, the rotation driving unit is provided with button hook positions matching with the claws, the central iron shaft pushes the powder outlet opening part to allow the sealing part to move relative to the connection driving part, and the first powder outlet overlaps the second powder outlet. The cartridge drive unit has no need of arranging a release structure, simplifies the structure, and reduces the cost.