The invention discloses an independent power supply system of hydrogen fuel cell. The system comprises a closed shell, a display and a three-layered metal frame; a hydrogen fuel cell galvanic stack, a hydrogen storage bottle and a radiator fan are arranged at the bottom layer of the three-layered metal frame; an inverter and a gas passage control element are arranged at the middle layer of the three-layered metal frame; the inverter is electrically connected with the gas passage control element; a DC/DC (direct current/direct current) converter, a controller and a storage battery are arranged on the upper layer of the there-layered metal frame; the storage battery is electrically connected with the inverter, the DC/DC converter and the controller respectively; and the controller is electrically connected with the display, the radiator fan and the air passage control element respectively. The independent power supply system of the hydrogen fuel cell provided by the invention can overcome the defects that in the prior art, the structure is unreasonable, the thermal radiation is large, the specific power is low, the air supply is single, the carrying is inconvenient and the like, and realize the advantages of reasonable structure, small thermal radiation, high specific power, much air supply and convenience in operation.