The present invention discloses a vacuum glass sealing device. The device comprises an air extraction table, an upper pressing plate and a heating device, wherein the air extraction table is provided with an accommodating groove for placing glass plates to be sealed, the upper pressing plate is pressed on the glass plates to be sealed in the accommodating groove and air-tightly connected with the air extraction table around the periphery of the accommodating groove; and the air extraction table and/or the upper pressing plate are provided with air extraction ports, and the heating device heats the glass plates to be sealed from the exterior. The air extraction table and the upper pressing plate form a closed space in the sealing device, and the upper pressing plate is directly pressed on the glass plates to be sealed, so the volume of the closed space is greatly reduced, and conditions are created for quick vacuumizing of the closed space and quick sealing of the vacuum glass. The closed space in the sealing device is only used for providing a vacuum environment, and the heating device for welding is separately arranged at the exterior, so equipment operation is convenient, equipment construction is simplified, and a condition is created for large-scale processing of the vacuum glass.