The invention provides an experiment cabin system capable of adjusting atmospheric environmental pressure. The system is characterized by comprising an experiment cabin arranged in a constant-temperature constant-humidity environmental chamber and a positive and negative pressure generation unit, a ventilation adjusting unit, an air purification unit, a meteorological sensor and a system control unit controllable both in and out of the cabin, which are arranged to be communicated with the cabin. Compared to the prior art, the invention has the following advantages: 1, the system can realize control of the environment condition of atmospheric pressure in research and experiments on tobacco and is applicable to control of atmospheric pressure in most regions where people live; 2, the inner space of the system is great, which enables a plurality of staff to simultaneously carry out experiments; 3, the comprehensive air purification unit is provided in the cabin, which enables collection and purification of harmful gas generated after combustion of tobacco to be realized; 4, the system is simple to operate and enables single-key operation and comprehensive information prompting to be realized in normal usage; and 5, security design and humanized design of the system are considerate, an automatic safety device is arranged in the cabin, and hand-operated safety devices are arranged in and out of the cabin.