The invention provides an excitation circuit of a transducer array of a three-dimensional acoustic wave downhole instrument. The circuit comprises a plurality of sealed multi-channel high-voltage electronic units positioned in a transmission sonic system, and each multi-channel high-voltage electronic unit comprises a bus interface circuit, a command receiving and transmitting control circuit and a plurality of excitation channels, wherein the bus interface circuit is connected with a transmission master control electronic unit in the three-dimensional downhole instrument and used for receiving a control command sent by the transmission master control electronic unit; the command receiving and transmitting control circuit is connected with the bus interface circuit and used for decoding the received control command and generating a transmission control logic signal according to the received control command; and the plurality of excitation channels are connected between the command receiving and transmitting control circuit and the transmission transducer array in parallel and used for generating a driving signal to realize excitation of the transducer array. The excitation circuit disclosed by the invention can solve the connection between a three-dimensional acoustic logging excitation electronic system and the transmission transducer array under downhole high temperature and narrow space conditions and further solve the problem of a command interface with the transmission master control electronic unit.