The invention provides a syringe assembly having a flexible or slidable flange. A syringe assembly (10) having a flexible (12) and/or slidable (212) flange is provided, wherein in a pre-use or packaged state, the flange is positioned substantially parallel to the barrel of the syringe resulting in a syringe assembly having a smaller packaging footprint. The smaller packaging footprint allows for reduced storage space of the syringe assembly. Upon removal from the packaging and/or storage space, the flange can be slid and locked into place such that it extends in a perpendicular direction with respect to a longitudinal axis of the syringe barrel to allow for traditional operation of the syringe.