The invention provides a method for blocking water for a fracture and hole type reservoir, which is particularly applicable to high-mineralization fracture and hole type reservoirs. The method includes that blocking agent with following ingredients is selected, the ingredients of the blocking agent include, by mass percent, from 5.24 to 9.36% of cement, from 3.03 to 5.35% of microsilica, from 4.01 to 5.43% of sodium bentonite, from 0.52 to 0.55% of polymeric dispersant, from 0.17 to 0.40% of retarder, from 0.0008 to 0.0011% of sodium carbonate aqueous solution by sodium carbonate and the balance water, and water cement ratio of the blocking agent ranges from 4.07 to 6.28; the blocking agent is injected into an oil well according to output volume of 300-800L/min, and after soaking for 72 hours, the well is opened and begins production; and the use level of the blocking agent is equal to 1/2 to 2/3 of the use level of fracturing liquid during acid-fracturing of an analog crack or communication of reservoir bodies, and is calculated by 5-20m3/m of a blocking well section for a well without being in acid-fracturing. The density of the blocking agent ranges from 1.09g/cm3 to 1.14g/cm3 and is not changed before and after solidification, solidification strength ranges from 0.22 MPa to 0.43MPa, leakage of the blocking agent due to the density reason cannot be caused in a water blocking process of the fracture and hole type reservoir, and the blocking agent can effectively stay on an oil-water boundary, and selectively blocks a water outlet channel.