The invention discloses a fully automatic hot fix rhinestone layout machine in the technical field of garment processing equipment. The fully automatic hot fix rhinestone layout machine comprises a machine frame, wherein an uncoiling device and a material collecting device are arranged on the machine frame, at least one group of layout assemblies is sequentially arranged between the uncoiling device and the material collecting device, each layout assembly comprises a hopper and a roller, the hopper is arranged on the machine frame, the roller is rotatablely arranged on the machine frame, in addition, the bottom of the roller extends into the hopper, magnetic rhinestone absorption holes are arranged on the circumferential surface of the roller, the roller rotates and absorbs magnetic hot fix rhinestones in the hopper into the magnetic rhinestone absorbing holes in a magnetic absorption method, a hot fix tape of the uncoiling device is peeled off, a transparent adhesive tape is covered on the top surface of the roller, the hot fix rhinestones are pasted and connected onto the adhesive surfaces of the transparent adhesive tape along with the rotation of the rolling tube and the movement of the transparent adhesive tape, one kind of layout of the hot fix rhinestones is completed in such a way, the transparent adhesive tape is continuously moved to a next group of layout assemblies for carrying out the other kind of layout of the hot fix rhinestones, finally, the transparent adhesive tape glued and connected with the hot fix rhinestones is pasted with white bottom paper for completing the hot fix rhinestone layout work, the fully automatic operation is adopted in the whole process, and the production efficiency is high.