The invention discloses a method for manufacturing a waterproof and burglarproof door with mortise lock pins. According to the method, a door leaf, a groove type lock base and a mechanism thereof, a lock control device, a door frame and convex lock lugs matched with the door frame are provided. The method is characterized in that grooves of the groove type lock base are formed on the opening side of the door leaf; groove exposure punched holes and the grooves are correspondingly formed; groove shapes are formed on the edge of the door leaf; the mortise lock pins are arranged in lock pin through holes formed in the groove type lock base and driven by transmission guide pieces on the groove type lock base to move back and forth in the grooves; the transmission guide pieces are connected with stress shaft pieces of the lock control device on the door leaf; the convex type lock lugs are arranged on the door frame corresponding to the grooves on the door leaf; and when the door leaf and the door frame are closed, the convex lock lugs are inserted into the grooves, so that the lock pins are prohibited from entering lock holes of the convex type lock lugs inserted into the grooves or are unlocked and retreated only by rotating a lock cylinder driving mechanism, which can drive the mortise lock pins in the lock pin through holes through the transmission guide pieces, of the lock device through a key.