The invention provides a Chinese medicinal granula for preventing and controlling coccidiosis in chickens and a preparation method of the Chinese medicinal granula. The Chinese granula is prepared from the following raw materials by weight: 2-5 parts of pumpkin seed, 1-4 parts of fruit of rangoon creeper, 1-2 parts of stone-like omphalia and 1-2 parts of rheum officinale, by the steps of decocting and mixing with auxiliary materials. The Chinese medicinal granula is based on reasonable proportioning of traditional Chinese medicines, is a medicine with effective treatment effect on coccidiosis in chicken and has the characteristics of quick acting, definite treatment effect, no residue and no toxic or side effect. The preparation method is simple and meets the requirement of large-scale industrial production.