The invention relates to an economical dispatch control system for a cascade power station. The system is characterized in that a host server, a history server and a voice workstation serve as an engineering work station, and an operator workstation, a large-screen projection and a GPS (Global Positioning System) system are connected in parallel on a main control line; and through the reverse regulation of an upper-level large capacity power station by a small capacity power station, a load difference is safely and smoothly transferred to another adjustable power station. By using the economical dispatch control system for the cascade power station provided by the invention, the flow of an upper-level power station unit can be effectively controlled through the flow of a lower-level power station; the water rate is lowered, the economic benefit of the power station is increased, the cost recovery time is effectively reduced, and thus the current low-carbon economic development trend is conformed to.