The invention discloses an acupoint plaster for treating spontaneous perspiration and night sweat. The acupoint plaster is prepared from the following components by weight: 9-11g of Chinese mahonia leaves, 9-11g of panicled fameflower root, 4-6g of halloysitum rubrum, 9-11g of Chinese gall, 9-11g of blighted wheat, 9-11g of processed rhizoma pinelliae, 9-11g of balausstine and 9-11g of oyster. The medicaments are grinded into fine powder, the fine powder is placed in a bottle for later use, a proper amount of prepared powder is fetched and uniformly mixed by honey to form a paste; and a proper amount of the paste is placed on a small piece of adhesive tape to be applied to two nipples for 24 hours, then the small piece of adhesive tape is taken down, another piece of adhesive tape is applied. When the acupoint plaster is applied once, the sweat becomes less in general; when the acupoint plaster is applied three times, the spontaneous perspiration and night sweat are substantially healed. The acupoint plaster for treating spontaneous perspiration and night sweat provided by the invention has the characteristics that use is convenient, curative effect is quick and curative rate is high.