The invention relates to a plaster for treating pain in waist and lower extremities. The plaster comprises the following raw materials in parts by weight: 8-12 parts of rhizoma drynariae, 8-12 parts of local achyranthes aspera, 8-12 parts of rhizoma cibotii, 8-12 parts of asarum, 8-12 parts of folium artemisiae argyi, 8-12 parts of ligusticum wallichii, 8-12 parts of galangal, 8-12 parts of radix angelicae tuhuo, 8-12 parts of gentian, 8-11 parts of fructus psoraleae, 8-11 parts of safflower carthamus, 8-11 parts of radix clematidis, 20-30 parts of cinnamon, 8-11 parts of scorpio, 8-10 parts of asteroid, 8-10 parts of Chinese angelica, 8-10 parts of raw kusnezoff monkshood root, 8-10 parts of eucommia bark, 8-10 parts of notopterygium root, 4-6 parts of long-noded pit viper, 3-6 parts of moghania macrophylla, 3-6 parts of wild grape vine, 3-6 parts of japanese stephania root, 3-6 parts of semen strychni, 12-14 parts of caulis lonicerae, 2-4 parts of pillis ophidiae, 2-4 parts of crude sichuan aconite root, 2-4 parts of centipede, 8-10 parts of boswellia carterii, 8-10 parts of myrrh, 10-12 parts of chaenomeles speciosa nakai, 1-3 parts of dragon's blood, 1-3 parts of brugmansia suaveolens, 0.5-2 parts of borneol, 5-8 parts of earthworm and 0.5-2 parts of clove. All raw materials are crushed to make the plaster to be applied to a painful place, and the plaster is changed every day. The plaster provided by the invention can be used for treating various types of pain in waist and lower extremities, is prepared from pure Chinese medicinal herbs without side effects, and is good in treatment effect and high in curing rate.