The invention discloses a solid-liquid waste and sewage biological comprehensive treatment system and treatment method. The comprehensive treatment system comprises a liquid sewage concentrate device, a water treatment constructed wetland system, a solid waste crushing and slurrying device and an anaerobic biochemical treatment system. The solid-liquid waste and sewage biological comprehensive treatment system and treatment method can simultaneously treat solid and liquid wastes, can fully utilize the solid and liquid wastes as energy resource and fertilizers, and compared with the existing treatment mode, have the advantages of being strong in concentricity, realizing more thorough utilization of wastes, lowering the treatment cost, producing benefits, and removing the bad influence on the ambient environment due to the existing waste treatment mode; the solid-liquid waste and sewage biological comprehensive treatment system and treatment method are commonly applicable to harmless treatment to municipal solid waste, domestic sewage, rural cultivation excrement, agricultural planting wastes and forest growth wastes, the solid-liquid waste and sewage biological comprehensive treatment system is of productive engineering facility taking the wastes as production raw material resources, the products include clean gas energy, biological organic fertilizer and recyclable water, thus being capable of changing wastes into valuables, and being beneficial to protection of the biological environment.