The invention relates to a manufacturing method of a photocatalyst-containing tile used for a wall surface. The method comprises: compressing tile powder for moulding, then controlling the temperature at 60-90DEG C and conducting drying for 40-70min, then placing the dried moulded powder into a firing furnace, controlling the temperature at 1000-1200DEG C and carrying out firing for 40-90min, then performing surface treatment and drying, finally spraying a nanometer photocatalyst solution on the surface of a green tile, controlling the temperature at 60-90DEG C, and implementing drying treatment so as to the product. Compared with the prior art, the invention adopts an appropriate photocatalyst material, solves the technical problem of applying a photocatalyst in tiles, and enable the photocatalyst to be applied in outer wall and inner wall products. Thus, the manufacturing method has a wide application scope.