The invention discloses a pharmaceutical composition preparation for treating nutritional anemia, and a preparation method thereof. The pharmaceutical composition preparation comprises radix astragali, arillus longan, angelica, donkey-hide gelatin, ferrous gluconate, brown granulated sugar, and auxiliary materials, and is mainly used for treating and improving nutritional anemia. Compared with the prior art, the pharmaceutical composition preparation of the invention is safe in use, definite in therapeutic effect, simple in prescription, simple in manufacturing process, and suitable for industrial mass production.