The invention relates to a method of constructing an ecological revetment for intensively intercepting and clearing non-point pollution based on organisms, which comprises the steps of investigating hydrologic conditions of a river, determining non-point pollution load and hydraulic retention time of a riparian zone in a unit length, analyzing characteristics of the non-point pollution along the river, screening a high-efficiency bacterium which can efficiently remove the non-point pollution or constructing gene engineering bacteria capable of removing nondegradable organic pollutants, constructing hollow hexahedral ecological revetment members, and growing plants in the members, thereby constructing the ecological revetment. Compared with the prior art, with the adoption of the method, the non-point pollution, particularly the nondegradable organic pollutants, can be removed effectively, the river pollution load can be decreased, potential ecological risks of the non-point pollution to a river ecosystem are reduced, and local raw materials are utilized to improve the environmental compatibility of the members, so that good habitat conditions are provided for the growth of microbial communities and vegetations at the riparian zone, and the mechanical stability of the riparian zone is improved.