The invention belongs to the field of animal medicine, and relates to a veterinary drug, particularly to a traditional Chinese drug composition capable of replacing antibiotic to prevent and treat piglet digestive tract bacterial diseases. The traditional Chinese drug composition comprises the following components, by weight, 10-25 parts of catclaw buttercup root tuber, 10-25 parts of lightyellow sophora root, 1-5 parts of tobacco shred, 5-10 parts of chrysanthemum, 20-30 parts of saruma henryi, 10-40 parts of coptis chinensis, and 5-40 parts of heartleaf houttuynia herb. The traditional Chinese drug composition of the present invention has the following advantages that: (1) a new compound traditional Chinese drug preparation capable of replacing the antibiotic to prevent and treat piglet digestive tract bacterial diseases is developed for veterinary clinic; (2) the formulation is reasonable, and the selected drugs are screened by carrying out systemic combination drug sensitive tests based on in vitro drug sensitive tests of 500 pig digestive tract separation pathogens; (3) the traditional Chinese drug composition has characteristics of safety, efficiency, low toxicity, low residue, and easy use; and (4) the production process is simple, the preparation is stable, the dose is accurate, and the quality is controllable.