The invention provides a pharmaceutical compound preparation for treating livestock respiratory diseases and a method for preparing the pharmaceutical compound preparation for treating livestock respiratory diseases. The pharmaceutical compound preparation consists of exocarpium citri grandis extract, poria extract, radix glycyrrhizae extract and water-soluble florfenicol, wherein the exocarpium citri grandis extract accounts for 8-15 parts by weight, the poria extract accounts for 2-10 parts by weight, the radix glycyrrhizae extract accounts for 1-5 parts by weight, the water-soluble florfenicol accounts for 5-20 parts by weight, and the pharmaceutical compound preparation is prepared through a mixing mode. According to the pharmaceutical compound preparation for treating livestock respiratory diseases, traditional Chinese medicine and western medicine are reasonably compounded, so that the effective treatment drug for preventing livestock respiratory diseases is provided for the breeding industry; the pharmaceutical compound preparation has the functions of relieving coughs and asthma, resisting bacteria and virus, improving the immunity of the organism and the like and treats both the manifestation and root causes, the curative process is shortened, and the occurrence probability of drug resistance is greatly reduced; and the method for preparing the pharmaceutical compound preparation is simple, is convenient to use and meets the requirements of mass industrial production.