The invention discloses a wiring device of a light-emitting diode (LED) display screen. The wiring device comprises the display screen, a male base and a female base are respectively arranged on two opposite sides of the display screen, the female base is embedded in the lateral wall of one of the two opposite sides of the display screen, a plurality of counter bores are arranged in the female base and respectively serve as a counter bore type power interface and a counter bore type signal interface, and openings of the counter bore type power interface and the counter bore type signal interface both face outwards. The male base is embedded in the lateral wall of the side opposite to the side where the female base is located, a pair of sliding rails is respectively arranged on two sides of the male base, the male base is located on the sliding rails, a plurality of elongated power interfaces and a plurality of elongated signal interfaces which both extend outwards are arranged in the male base, a push handle is fixedly arranged on the male base and protrudes out the surface of the display screen, and an elongated hole for the push handle to be pushed back and forth is arranged on the surface of the display screen. The wiring device achieves connection of a power line and a signal line simply by pushing the push handle, is convenient to install, saves an outside connection wire and a corresponding joint, and reduces product cost.