The invention relates to a high-barrier composite hose which comprises a hose body, a hose shoulder and a cap cover, wherein a hose wall of the hose body is provided with a barrier layer; the barrier layer is a PVA (Polyvinylalcohol) coating; preferably, the hose wall of the hose further comprises a printing layer, an outer adhesive layer, an inner adhesive layer and a heat sealing layer; the printing layer, the outer adhesive layer, the barrier layer, the inner adhesive layer and the heat sealing layer are sequentially bonded from the outside in; the hose wall of the hose body further comprises an oil ink layer; the oil ink layer is positioned between the printing layer and the outer adhesive layer and bonded with the printing layer and the outer adhesive layer respectively, or is positioned outside the printing layer and bonded with the printing layer; the hose shoulder is mounted on the hose body; and the cap cover is arranged on a hose orifice of the hose shoulder in a covering manner. The invention further relates to a manufacturing method of the high-barrier composite hose. The high-barrier composite hose is high in barrier property, convenient to process, low in production cost, and suitable for large-scale popularization and application, and the barrier property is improved comprehensively.