The invention discloses an interval type-2 fuzzy geographic area topological relation determining method based on an IT2 FS (interval type-2 fuzzy set). A topological relation analysis system is constructed by adopting multi-scale remotely sensed data and a fuzzy geographic entity model. The distribution range of fuzzy geographic targets is extracted from the multi-scale remotely sensed data. However, the distribution range cannot be accurately defined and can only be expressed by adopting a fuzzy method. An interval type-2 fuzzy mathematical model is used for expressing the possible distribution range of the geographic targets. An interval type-2 fuzzy topological relation computing system consists of an interval type-2 fuzzy geographic area extraction module, an interval type-2 fuzzy boundary extraction module and an interval type-2 fuzzy position topological relation computing module. The multi-scale remotely sensed data enters the system, the fuzzy distribution range is extracted and the boundary area of the distribution range is extracted. The interval type-2 fuzzy position topological relation computing module conducts analysis by using the fuzzy distribution range, the boundary area and data such as houses and towns to obtain a fuzzy analysis result, so as to realize the computation of the fuzzy position topological relation.