The invention discloses prostate treatment granules and a preparation method thereof. According to a formula, the prostate treatment granules are prepared by the following raw materials: 10-30 g of caulis akebiae, 5-15 g of angelica, 5-15 g of astragalus mongholicus, 5-15 g of radix angelicae, 5-15 g of cowherb seed, 5-15 g of beautiful sweetgum fruit, 5-15 g of radix achyranthis bidentatae, 5-15 g of immature bitter orange, 5-15 g of rhizoma phragmitis and 5-15 g of poria cocos. The preparation method comprises the steps of grinding and packaging to obtain the prostate treatment granules. The prostate treatment granules have the advantages that the raw materials are easy to obtain, the preparation is easy, the use is convenient, the effect is good and the like.