Disclosed is a combustor fuel injection and mixing device. A main combustion level, a middle combustion level, and a pre-combustion level are sequentially arranged from outside to inside of the combustor fuel injection and mixing device. Fuel respectively flows into oil pipelines of the main combustion level, the middle combustion level and a pre-combustion level through a main combustion level oil inlet hole, a middle combustion level oil inlet hole and a pre-combustion level oil inlet hole. The fuel in the oil pipelines are injected into a main combustion level channel, a middle combustion level channel and a pre-combustion level channel through a main combustion level nozzle, a middle combustion level nozzle and a pre-combustion level nozzle. The main combustion level nozzle is a pre-film type nozzle. Wall surface of two sides of the main combustion level nozzle is an assembling surface for assembling. The main combustion level oil pipe after a curve section is gradually expanded into a slit to enable the fuel in the main combustion level oil pipeline to form a layer of oil film behind the outer side wall of the main combustion level nozzle. Swirler components capable of shearing and atomizing the fuel injected into the main combustion level channel under the act of swirling are arranged around the main combustion level nozzle. The combustor fuel injection and mixing device is capable of improving mixture evenness of fuel and gas in the main combustion level and further improving temperature distribution of the outlet of the combustor.