The invention relates to a heterogeneous network interference coordination method on the basis of carrier aggregation. Due to consideration on that interference to Pico edge users is the most serious, and thus, the carrier aggregation characteristic is utilized to enable macro station not to send a control signaling on control channels of part of composition carriers and according to scheduled user information with the worst SINR (Signal Interference Noise Ratio) in the Pico edge users, transmission power of the macro station on data channels of the part of composition carriers is reduced, so that interference of the macro station to the control channels and the data channels of the Pico edge users is reduced to a great degree. Moreover, due to consideration on that reduction of the transmission power of the macro station on part of composition carriers possibly causes reduction of throughput of the macro station, by a cost function consisting of throughput loss of macro users and a throughput gain of the Pico edge users, the data channel transmission power of the macro station on the composition carriers which provide interference protection is determined, so that while the throughput of the Pico edge users is improved, the throughput loss of the macro station is reduced and the total throughput of a system is promoted.