The invention relates to a preparation method of a traditional Chinese medicine lotion for acute mastitis caused by capsicum adephagia, which belongs to the traditional Chinese medicine preparation method technical field. Currently, the treatment for acute mastitis caused by capsicum adephagia generally employs sulfonamides and antibiotics, and the disadvantage of the antibiotics and sulfonamides is large side effect. A technical scheme is characterized in that saururus chinensis, root of chinese barberry, folium isatidis, garden euphorbia herb, desmodium, Rohdea japonica Roth, Aster ageratoides, bushy sophora, cremastra, senecio, huperzine serrate, Stephania rotunda lout, thymifoious euphorbia herb, Meadowrue Root and Rhizome, purslane, Coriaria sinica Maxim, areca peel, sun spurge, spirifer, Sphenomorphus indicus, Nerium odorum, exocarpium benincasae, red bean, Zanthoxylum bungeanum Maxim, corn silk, cucurbit, Commelina communis L, Polygonum aviculare, fringed pink, akebia stem, ricepaperplant pith medulla tetrapanacis, Tokyo violet herb and licorice are taken, the above traditional Chinese medicines are placed in water for immersing, and then decocted by slow fire, filtered to remove the slag, and the decocted soup is the traditional Chinese medicine for treating acute mastitis caused by capsicum adephagia. The prepared traditional Chinese medicine has the advantages of small toxic and side effects, short treatment course and high cure rate.