The invention relates to a preparation method of a traditional Chinese medicine for treating liver depression type acute mastitis, which belongs to the traditional Chinese medicine preparation method technical field. Currently, the treatment for treating liver depression type acute mastitis generally employs antibiotics and sulfonamides, and the disadvantage of the antibiotics and sulfonamides is large side effect. A technical scheme is characterized in that radix bupleuri, Cyperus Rotundus L, curcuma tuber, radix gentianae, celosia seeds, butterflybush flower, pipewort, scouring rush, chrysanthemum, mint, periostracum cicadae, areca peel, semiaquilegia root, akebia stem, corn silk, pyrrosia lingua, spirifer, skink, white gourd peel, Semen Abutili, broom cypress fruit, oleander, Persicaria perfoliata, junci medulla, Jiangxi desmodium, Caulis aristolochiae manshuriensis, red bean, desmodium, oriental waterplantain rhizome, sun spurge, Poria cocos, fingered citron and licorice are taken, the above 33 traditional Chinese medicines are placed in water for immersing, and then decocted by slow fire, filtered to remove the slag, the decocted soup is the traditional Chinese medicine lotion for treating liver depression type acute mastitis. The prepared traditional Chinese medicine has the advantages of small toxic and side effects, short treatment course and high cure rate. The adverse reaction generated by western medicine can be avoided.