The invention relates to an adjusting mechanism of trimming squirts used for cutting paper. According to the adjusting mechanism, an indicating plate is fixedly arranged on a support which is provided with a slider capable of sliding left and right on the surface of the support, an inner water inlet pipe and an outer water inlet pipe are fixed on the slider, the squirt is arranged on one end portion of each water inlet pipe, scale marks matched with the indicating plate are arranged on each water inlet pipe, a lead screw is rotatably connected on the support, two ends of the lead screw are rotatably arranged on the support, the lead screw is connected in a screw hole in the slider in a screwed mode, a hand wheel is arranged on the end portion of the lead screw, and a locking device used for fastening the lead screw and the support into a whole is arranged on the lead screw. When the width of a paper web is adjusted, a method that a fastening bolt is loosened by hands is changed to the method that the hand wheel is used for rotation, the adjustment is convenient, adjusting time of workers is greatly saved, and work efficiency is improved.