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发明公开
CN103125445A 一种1号染色体替换实验小鼠品系C57BL/6-Chr1NZW的构建 失效 - 权利终止

一种1号染色体替换实验小鼠品系C57BL/6-Chr1NZW的构建
摘要：
本发明涉及一种1号染色体替换实验小鼠品系C57BL/6-Chr1NZW的构建。本发明构建了一种新的染色体替代实验小鼠品系，该小鼠品系的遗传背景以C57BL/6小鼠为主，但其中1号染色体来自于NZW小鼠。本发明的染色体替换品系可用于研究在相同基因组背景下，由不同的1号染色体基因组带来的性状差异，是采用遗传学方法研究染色体基因组功能的有用工具。
摘要（英）：

The invention relates to construction for a number 1 chromosome substitution laboratory mouse strain C57BL/6-Chr1NZW. According to the construction for the number 1 chromosome substitution laboratory mouse strain C57BL/6-Chr1NZW, a new chromosome substitution laboratory mouse strain is constructed. A genetic background of the chromosome substitution laboratory mouse strain is based on a C57BL/6 mouse, while wherein a number 1 chromosome is from an NZW mouse. According to the construction for the number 1 chromosome substitution laboratory mouse strain C57BL/6-Chr1NZW, the chromosome substitution laboratory mouse strain can be used for research of character differences brought by different number 1 chromosome genomes under the same genome background, and can be a useful tool for research of the chromosome genome functions by adoption of a genetic method.

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