The invention relates to a compound filling pottery clay capable of sterilization. The compound filling pottery clay is prepared by a special process. The compound filling pottery clay can be applied in the fields such as ceramic products, automobile tires, rubber products, food inner packages, plastic products, building and decoration coatings, etc. The compound filling pottery clay can be used for preparing filling materials for sterilization and antibiosis products. The compound filling pottery clay can be made into products with different specifications according to shapes and applications, is used for deterioration and decomposition caused by polluted bacteria during processes of product storage and transportation, and has the functions of removing peculiar smell, preventing mildew, sterilizing, preventing decomposition, resisting poisons, etc.