Provided are a compound type photocatalyst air purification waterborne interior wall coating and a preparation method thereof. The compound type photocatalyst air purification waterborne interior wall coating comprises, by weight, the following materials of 5.5-22.3% of photocatalysis packing, 25-65% of polyurethane emulsion, 1-6% of propylene glycol phenylate, 2-6% of dispersing agents, 2-4% of stabilizing agents, 1-2% of wetting agents, 20-60% of water, 1.5-4% of mildewproof agents, 1-2% of antifoaming agents, 0.5-2% of flatting agents, and 0.5-1% of thickening agents. The photocatalysis packing is formed by complexation of nanoanatase type titanium dioxide and nano-zinc oxide or nano stannic oxide according to a weight ratio of 5-9:1-5. The coating has good air purifying capacity, and can effectively degrade harmful gases in the air and kill bacterial viruses under excitation of ultraviolet light. As an interior decorative material, the coating has good covering power and adhesive power and excellent stability. The coating and the production method are simple in production process, suitable for various coating methods, and easy to popularize and apply.