The invention discloses a residential quarter handover decision and a related device. The residential quarter handover decision and the related device are used for solving the problems of coverage balance and interference in a collaborative networking scenario of an existing macro base station and a microcellular base station. The residential quartet handover decision method comprises the following steps: receiving a path loss measurement result reported by unified equipment (UE), wherein the path loss measurement result comprises the path loss of a serving residential quarter and the path loss of the adjacent residential quarter which meets the reported conditions of the path loss; and according to the path loss measurement result, choosing the adjacent residential quarter which meets screening conditions of a target residential quarter as a target residential quarter cluster, if the path loss of the servicing residential quarter is higher than a decision threshold of the path loss of the servicing residential quarter, and then choosing the residential quarter which has the best path loss condition as a handover target residential quarter from the target residential quarter cluster.