The invention provides a self-repairing compound titanium-based lubricating grease and a preparation method thereof, and relates to a lubricating grease and a preparation method of the lubricating grease. The lubricating grease has excellent antioxidant ability and bearing capacity, and is capable of repairing the surface of a wearing part and prolonging the service life of the friction part. The lubricating grease is prepared by mixing a base oil, a compound titanium soap thickening agent, an antioxidant additive, an anti-wear reagent at extreme pressure, an antifriction additive and a self-repairing lubricating material together; and the preparation method of the lubricating grease comprises the following steps of mixing the base oil with a high molecular acid and stirring, heating the temperature to the range of 80-90 DEG C, adding tetraisopropyl titanate and a low molecular acid, preserving heat and stirring, increasing the reaction temperature to the range of 120-150 DEG C, and then adding the left base oil and continuing increasing the temperature to the range from 200 to 220 DEG C and stirring; adding the self-repairing lubricating material after grease is formed, and stirring, and then adding other additives, and finally, grinding, homogenizing and degassing, thereby obtaining the self-repairing compound titanium-based lubricating grease. The self-repairing compound titanium-based lubricating grease is used for the automobile industry, the metallurgical industry, the food industry and the aircraft industry.