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发明公开
CN103173449A 与食管癌术后早期复发和预后相关的miRNA标志物及其应用 有权 转让

与食管癌术后早期复发和预后相关的miRNA标志物及其应用
摘要：
本发明公开了与食管癌术后早期复发和预后相关的miRNA标志物及其应用，其中，miRNA标志物为has-miR-382。该miRNA标志物在制备食管癌术后早期复发和预后辅助诊断试剂盒方面的应用。一种与食管癌术后早期复发和预后相关的miRNA标志物的引物在制备食管癌术后早期复发和预后辅助诊断试剂盒方面的应用。一种与食管癌术后早期复发和预后相关的miRNA标志物的引物的食管癌术后早期复发和预后辅助诊断试剂盒。本发明方法简单、操作方便，筛选得到的has-miR-382可辅助判断食管癌患者的预后或死亡风险，推动了食管癌诊治方面的发展。
摘要（英）：

The invention discloses an esophagus cancer postoperative early-stage recurrence and prognosis related miRNA marker and its application, and concretely discloses an miRNA marker has-miR-382, an application of the miRNA marker in the making of an esophagus cancer postoperative early-stage recurrence and prognosis auxiliary diagnosis kit, an application of the primer of the esophagus cancer postoperative early-stage recurrence and prognosis related miRNA marker in the making of the esophagus cancer postoperative early-stage recurrence and prognosis auxiliary diagnosis kit, and the esophagus cancer postoperative early-stage recurrence and prognosis auxiliary diagnosis kit of the primer of the esophagus cancer postoperative early-stage recurrence and prognosis related miRNA marker. A screening method in the invention is simple and is convenient to operate, and the screened has-miR-382 can auxiliarily determine the prognosis or death risk of an esophagus cancer patient, and promotes the development of the esophagus cancer diagnosis and treatment.

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