利索-全球专利检索

  1. 登录
  2. 注册
发明公开
CN103200956A 具有稳定区域的GLP-1受体激动剂化合物 无效 - 撤回

具有稳定区域的GLP-1受体激动剂化合物
摘要：
本发明内容提供具有相当于天然肽化合物的α-螺旋区的稳定区域的GLP-1受体激动剂化合物。本发明内容还提供含苯甲酰胺的毒蜥外泌肽-4类似物和烯烃受约束的毒蜥外泌肽-4类似物，两种类似物具有相当于毒蜥外泌肽-4的α-螺旋区的稳定区域。
摘要（英）：

The disclosure provides GLP-1 receptor agonist compounds having stabilized regions corresponding to alpha-helical regions of the natural peptide compounds. The disclosure also provides benzamide-containing exendin-4 analogs and alkene-constrained exendin-4 analogs, both of which have stabilized regions corresponding to alpha-helical regions of exendin-4.

0/0