The invention relates to a preparation method of an antisepsis and anti-inflammation lubrication-type condom containing natural cinnamyl aldehyde. The preparation method of the antisepsis and anti-inflammation lubrication-type condom containing natural cinnamyl aldehyde particularly comprises the following steps of: coating cinnamyl aldehyde directly on a natural emulsion condom or butyronitrile emulsion condom finished product, or adding and dispersing a certain amount of cinnamyl aldehyde together with other conventional burdening uniformly into the natural emulsion or butyronitrile emulsion in raw material prevulcanization process of the natural emulsion condom or the butyronitrile emulsion condom; then steeping and forming a natural emulsion glove condom or a butyronitrile emulsion condom which comprises natural cinnamyl aldehyde by a conventional forming technology; and then performing edge curling, chloridizing, foam-washing, rinsing and drying, thereby obtaining a finished product. The condom prepared by the method has the function of antisepsis and anti-inflammation, lubricating and skin protection; and meanwhile cinnamyl aldehyde can emit fragrant flavor, and can eliminate peculiar smell secreted by human bodies, is simple in technology, is low in cost, also saves resources, and improves the production efficiency.